late 14c., "a musical sound, a succession of musical notes," unexplained variant of tone. Meaning "state of being in proper pitch" is from mid-15c.
"bring into a state of proper pitch," c.1500, from tune (n.). Non-musical meaning "to adjust an organ or receiver" is recorded from 1887. Verbal phrase tune in in reference to radio (later also TV) is recorded from 1913; figurative sense of "become aware" is recorded from 1926. Tune out "to eliminate radio reception" is recorded from 1908; figurative sense of "disregard, stop heeding" is from 1928. Related: Tuned; tuning.
To bring something, esp a car motor, to its best state of effectiveness; tinker with to improve: tuning up for the race at Santa Ana
[1901+; fr the process of tuning a musical instrument, suggested by the fact that the performance of motors can be gauged by their sound]